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Laboratory Corporation of America Scientist - Assay Development in South San Francisco, California

Monogram Biosciences, a wholly-owned subsidiary of LabCorp, is seeking an Assay Development Scientist to join its Process Development Operations (PDO) team South San Francisco, CA! The PDO group leads or assists with the development, validation and support of commercial diagnostic assays as well as pharmaceutical and academic-sponsored research programs, including clinical trial support. The group covers a wide variety of technologies (automation, molecular biology, cell biology, biochemistry) that are applied to a wide variety of research/disease areas (HIV infectious disease, HCV infectious disease, SARS-CoV-2 infectious disease, respiratory viruses, gene therapy, oncology, pharmacogenomics, neurology).

The Scientist will work within an integrated team responsible for design, development, scale-up and implementation of innovative assays and automated systems for high throughput molecular, biochemical, and cell-based assays that direct critical treatment decisions for patients suffering from life-threatening diseases.


  • Development and execution of experimental and validation protocols to facilitate introduction of new assays or assay improvements to Monogram's CLIA-accredited clinical laboratory and Companion Diagnostic laboratory

  • Collaboration with writing, editing, reviewing and development of Standard Operating Procedures (SOPs) and training of laboratory personnel on new or improved procedures in the clinical laboratory

  • Responsible for investigation, trouble-shooting, and documentation of situations arising in the production clinical laboratory setting

  • Participation in maintenance and trouble-shooting of laboratory instruments in both R&D and Production settings, including participation in off-hour on-call duties as needed


  • Ph. D. degree in Molecular Biology, Virology or related area of Biological Sciences required with a minimum of 1 year of relevant experience, preferably within biotech/pharma industry (Postdoctoral experience may serve as experience. OR M.S. degree with 5+ years' relevant biotech/pharma experience

  • Previous experience in assay development is required. Experience in developing and implementing process development strategies (workflow, capacity, quality) is desired

  • Experience in virology, biochemical, cell or molecular biology techniques is desired, including cell culture, cell based assays, nucleic acid amplification, molecular cloning and next generation nucleotide sequencing

  • Experience with CAP/CLIA and/or GMP/GLP guidelines is preferred

  • Experience with developing and maintaining instrumentation and high throughput systems is desired

  • Good organizational and data analysis skills. Ability to independently conduct and analyze critical experiments that further project goals

  • Ability to work within a highly collaborative environment. Ability to function as a key liaison with members of other departments to effectively implement, train, support and troubleshoot clinical processes.




Monday - Friday, 8am-5pm

As an EOE/AA employer, the organization will not discriminate in its employment practices due to an applicant's race, color, religion, sex, national origin, sexual orientation, gender identity, disability or veteran status.